I believe so. You'll find this solution documented by various people in various places, for example:
http://www.coldfusionmuse.com/index.cfm/2009/10/27/registry.bad.dataso urce.good
So what we did was two things: 1) Change the Session storage from the registry to MS SQL. 2) Remove the reference in the XML file (neo-clientstore.xml) to registry session storage, as documented in the attached link.
That fixed it for us. It's been over a month and so far so good.
Chuck